Visualizing nanoparticle surface dynamics and instabilities enabled by deep denoising

Peter A. Crozier, Matan Leibovich, Piyush Haluai, Mai Tan, Andrew M. Thomas, Joshua Vincent, Sreyas Mohan, Adria Marcos Morales, Shreyas A. Kulkarni, David S. Matteson, Yifan Wang, Carlos Fernandez-Granda

Science 2025

Paper

This collaboration uses unsupervised deep denoising to study fast structural changes in nanoparticles through electron microscopy.

My research at New York University focused on evaluating denoisers without clean ground truth, using unsupervised estimates of MSE and PSNR.